KCNK18 抗体
Quick Overview for KCNK18 抗体 (ABIN5698029)
抗原
See all KCNK18 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- KCNK18 antibody
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免疫原
- potassium channel, subfamily K, member 18
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亚型
- IgG
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anti-Potassium Channel Subfamily K Member 18 (KCNK18) (AA 62-75), (Extracellular) antibody
KCNK18 适用: 小鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Subfamily K Member 18 (KCNK18) (AA 168-197) antibodyKCNK18 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33126 unconjugated
anti-Potassium Channel Subfamily K Member 18 (KCNK18) (Center) antibodyKCNK18 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))
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别名
- KCNK18
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背景
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Synonyms: Potassium channel subfamily K member 18|TWIK-related individual potassium channel|TWIK-related spinal cord potassium channel|KCNK18|TRESK|TRIK
Background: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation(By similarity).
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分子量
- 44 kDa
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基因ID
- 338567
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UniProt
- Q7Z418
抗原
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